General
Why this, why now
Why a couple of registered dietitians got tired of the marketing noise and just want to help people make better nutrition and supplement decisions.
Whitney Brooke Isola, MBA, RDN · · 1 min read
Built by Registered Dietitians
You’ve been told you’re fine.You know you’re not.
Supplement guidance built for you. Pragma accounts for your life stage, your hormones, and cuts through the noise to help get your body what it needs right now. Built by Registered Dietitians, with zero brand deals clouding the logic.
No credit card. No catch. Free to get started.
Foundation Stack
SampleMagnesium Glycinate
Evening · with foodChelated form
300mg
Progesterone decline in perimenopause impairs magnesium absorption and disrupts sleep architecture. Glycinate is the preferred chelated form: highest bioavailability, minimal GI side effects.
Rule #14Perimenopause · Sleep + mood
Indicated when progesterone is declining and at least two of: poor sleep, anxiety, muscle cramps, or fatigue are reported.
Brand picks
PremiumThorne Magnesium Bisglycinate
~$28 / 60 capsValueNOW Foods Magnesium Glycinate
~$14 / 180 capsAdapts with engagement, gets smarter as you go
Daily check-in· 60 sec
Built by healthcare professionals
We don't sell supplements
No brand bias, ever
Free to get started
Made specifically for women's bodies
Why Pragma exists
Women are told they’re fine. Generic supplement advice ignores life stage, hormones, medications, and individual needs. Pragma exists to bring clarity, evidence, and personalization to supplementation.
Who it's for
Your life stage is a first-class input.
Not a footnote. Not a modifier. Your body isn’t static. Your nutrition recommendations shouldn’t be either.
GLP-1 users
On semaglutide or tirzepatide?
GLP-1 drugs reduce appetite and accelerate nutrient depletion. Lean mass, bone density, B12, iron. The gaps compound quickly. Pragma builds your protocol around the specific depletion pattern.
Read our GLP-1 guides →On birth control
Years on the pill?
Combined contraceptives deplete B6, B12, folate, magnesium, zinc, and CoQ10 over time. Almost no prescriber mentions it. Pragma does, with a specific protocol to address it.
Postpartum
After pregnancy or nursing?
Your body ran a marathon for nine months. Ferritin, iodine, omega-3, choline. The recovery list is specific, and the stakes are real. Built from your labs, not a generic checklist.
Read our postpartum guides →Perimenopause
Sleep, brain fog, mood shifts?
Progesterone drops first. Estrogen clearance shifts. Magnesium, creatine, and targeted B-complex have real RCT evidence for what you’re experiencing. Let’s sequence them correctly.
Read our perimenopause guides →Our promise
Three rules we don't break.
The wellness industry is loud. Guidance you can actually trust is what makes Pragma different.
I
Clinically grounded
Every recommendation rule is built on top of high quality clinical protocols and evidence, reviewed by a Clinical Advisory Board, and embedded into the AI. Science first, fully auditable.
II
We don't sell supplements
We evaluate what's already on the market and tell you what's actually worth your money. If we link to a product, we tell you. Affiliate relationships never influence our recommendations, they just help keep Pragma free.
III
Built around your biology
Your hormonal context, life stage, recent body signals, and goals all shape what your body may need. Our recommendations are built around those inputs, then sequenced so you know what to start with and why.
How it works
A protocol that compounds with you.
Answer a few questions about your life stage and current routine. Pragma helps you understand what matters now, what to start with, and what to ignore.
1
Tell us where you are
Answer a few questions about your life stage and current routine.
2
Get your personalized stack
We match you with the supplements that matter for your specific situation, and flag the ones to skip.
3
Shop with confidence
We point you to quality products without pushing any brand. Mechanism first, not marketing.
4
Easy tracker
The system gets more precise as you track how you feel. As your needs change, we build on your stack.
Intake
A few quick questions
PerimenopauseGLP-1PostpartumOn the pill
Step 1 of 6 · about 60 seconds
Your stack
Personalized Foundation Stack
Magnesium Glycinate
300 mgOmega-3 (EPA/DHA)
1 gVitamin D3 + K2
2000 IUGeneric multivitamin
skipWhere to buy
Product recommendations
Thorne MagnesiumPremium
NOW Foods GlycinateValue
Ranked on dose, form & evidence. Never paid placement.
Tracker
How you’re feeling
Energy trending up across the last 7 days
Affiliate Disclosure: Pragma is brand-agnostic by design. We never sell our own supplements, and our affiliate relationships don’t change what we recommend; they help us keep the free tier free for you. Every recommendation is ranked on mechanism, dose, form, and evidence first. If a product has an affiliate link, it’s labeled.
Sound familiar?
We hear this constantly.
“I'm taking 6 supplements but I have no idea if any of them are actually doing anything.”
“My doctor said my bloodwork was fine, but I still feel exhausted all the time.”
“I started birth control years ago and nobody mentioned it could affect my nutrient levels.”
“Every supplement brand claims theirs is the best. I can't tell who to trust.”
“I'm postpartum and just want to know what I actually need, not a list of 20 things.”
“I wish someone could just tell me what's worth buying and what's a waste of money.”
Pragma was built for exactly these moments.
Pricing
Cut through the noise.
Feel clearer about what your body needs. Join Pragma for recommendations built around your life stage, daily patterns, and goals.
Start free
Pragma Free
$0· free
Your personalized Foundation Stack, built from your intake answers. No credit card required.
Personalized Foundation Stack
Daily check-in tracker
Monthly protocol reviews
Brand recommendations
Pragma Plus
$8/mo
Everything in Free, plus guidance that keeps pace as your body, labs, and goals change.
Everything in Pragma Free
Personalized supplement guidance
Ongoing recommendation updates
Priority protocol reviews
Pragma Premium
$22/mo
Everything in Plus, with advanced analysis for the deepest level of personalization.
Everything in Pragma Plus
Advanced genetic analysis*
Advanced lab analysis*
*Genetic testing and laboratory testing are external services and are not included in the subscription price.
From the journal
Latest from our Registered Dietitians
Evidence-first guidance on the questions women actually ask — written and reviewed by RDs, with no brand deals behind it.
Perimenopause
The four lifestyle levers most affecting your weight in your 40s (none of them are berberine)
The "everything I'm doing right stopped working" wall in your 40s is real, and it's not a metabolism that broke. Four levers explain most of it: muscle, protein, sleep and cortisol, and blood sugar. Here's the honest order to pull them.
Whitney Brooke Isola, MBA, RDN · · 6 min read
Perimenopause
Perimenopause: the underdiagnosed years before the diagnosis
Perimenopause can start a decade before menopause, and its early signs get filed under stress, anxiety, or aging. A clear guide to the transition, why it's missed, what to track, and the interventions (medical and nutritional) that actually help.
Samantha Peebles, DCN, RDN · · 6 min read
Meet the founders
Two Registered Dietitians who got tired of generic answers.
The day Pragma takes $1 from a supplement brand for a recommendation is the day every recommendation becomes suspect. So we don’t.
Whitney & Samantha
Their bodies were changing. Their needs were changing. But the recommendations weren’t. So we built Pragma to start where most wellness advice doesn’t: with the real physiological context of a woman’s current life stage.
One of us grew up watching a grandfather keep a careful supplement cabinet, taking micronutrition seriously long before it was fashionable. That early belief, that small, precise nutritional inputs compound over time, is the foundation Pragma is built on.
Every recommendation in Pragma is grounded in robust clinical evidence, built mechanism first, reviewed by our Clinical Advisory Board, and fully transparent about how it was made. We sign off on every rule. No black boxes.
Founder · MBA, RDN
Whitney Brooke Isola
Co-founder · DCN, RDN
Samantha Peebles
Questions
Good questions. Here are the honest answers.
Pragma is a nutrition guidance app for women navigating specific life stages: GLP-1 use, perimenopause, hormonal birth control, and postpartum recovery. We help you understand which supplements actually matter for your body right now, and which ones are just noise.
Free to get started
Get your personalized stack, free
Tell us what’s going on. Get a Foundation Stack built by Registered Dietitians, specific to your life stage and hormonal status. No credit card. No catch.
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